Chemicals and Drugs

VLDL Lipoproteins

A class of lipoproteins of very light (0.93-1.006 g/ml) large size (30-80 nm) particles with a core composed mainly of TRIGLYCERIDES and a surface monolayer of PHOSPHOLIPIDS and CHOLESTEROL into which are imbedded the apolipoproteins B, E, and C. VLDL facilitates the transport of endogenously made triglycerides to extrahepatic tissues. As triglycerides and Apo C are removed, VLDL is converted to INTERMEDIATE-DENSITY LIPOPROTEINS, then to LOW-DENSITY LIPOPROTEINS from which cholesterol is delivered to the extrahepatic tissues.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A class of lipoproteins of very light (0.93-1.006 g/ml) large size (30-80 nm) particles with a core composed mainly of TRIGLYCERIDES and a surface monolayer of PHOSPHOLIPIDS and CHOLESTEROL into which are imbedded the apolipoproteins B, E, and C. VLDL facilitates the transport of endogenously made triglycerides to extrahepatic tissues. As triglycerides and Apo C are removed, VLDL is converted to INTERMEDIATE-DENSITY LIPOPROTEINS, then to LOW-DENSITY LIPOPROTEINS from which cholesterol is delivered to the extrahepatic tissues.

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MeSH Record

Synonyms

24 entry terms
  • Lipoproteins, VLDL
  • Pre-beta-Lipoprotein
  • Pre-beta-Lipoproteins
  • Prebeta-Lipoprotein
  • Prebeta-Lipoproteins
  • Very Low Density Lipoprotein
  • Very-Low-Density Lipoprotein
  • Very-Low-Density Lipoproteins
  • Lipoprotein, Very-Low-Density
  • Lipoproteins, Very-Low-Density
  • Pre beta Lipoprotein
  • Pre beta Lipoproteins
  • Prebeta Lipoprotein
  • Prebeta Lipoproteins
  • Very Low Density Lipoproteins
  • Lipoprotein VLDL II
  • Lipoproteins, VLDL I
  • Lipoproteins, VLDL III
  • Lipoproteins, VLDL1
  • Lipoproteins, VLDL2
  • Lipoproteins, VLDL3
  • VLDL1 Lipoproteins
  • VLDL2 Lipoproteins
  • VLDL3 Lipoproteins

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

Indexing Annotation

hypoprebetalipoproteinemia = LIPOPROTEINS, VLDL /blood (IM) + HYPOLIPOPROTEINEMIAS (IM); /defic: consider also HYPOLIPOPROTEINEMIAS

MeSH Record

History Note

74(72); VERY-LOW-DENSITY LIPOPROTEINS was VERY LOW DENSITY LIPOPROTEINS 1972-95

MeSH Record

Previous Indexing

  • Lipoproteins (1966-1971)

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Tree Numbers

AMA Style

References

  1. National Library of Medicine. VLDL Lipoproteins. Medical Subject Headings (MeSH). 2026. Unique ID D008079. http://id.nlm.nih.gov/mesh/2026/D008079
  2. VLDL Lipoproteins. In: Wikipedia. https://en.wikipedia.org/wiki/Very_low-density_lipoprotein
  3. VLDL Lipoproteins. In: Wikidata. https://www.wikidata.org/wiki/Q419074