Structured Summary
Abstract
A proteolytic enzyme that converts PLASMINOGEN to FIBRINOLYSIN where the preferential cleavage is between ARGININE and VALINE. It was isolated originally from human URINE, but is found in most tissues of most VERTEBRATES.
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Classification
Broader headings
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MeSH Record
Synonyms
12 entry terms
- Plasminogen Activator, Urokinase-Type
- U-PA
- U-Plasminogen Activator
- Urinary Plasminogen Activator
- Urokinase
- U Plasminogen Activator
- Urokinase Type Plasminogen Activator
- Abbokinase
- Kidney Plasminogen Activator
- Renokinase
- Single-Chain Urokinase-Type Plasminogen Activator
- Single Chain Urokinase Type Plasminogen Activator
MeSH Record
Aspects Covered
29 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2009(1963)
MeSH Record
Previous Indexing
- Fibrinolytic Agents (1966-1974)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Urokinase-Type Plasminogen Activator. Medical Subject Headings (MeSH). 2026. Unique ID D014568. http://id.nlm.nih.gov/mesh/2026/D014568
- Urokinase-Type Plasminogen Activator. In: Wikidata. https://www.wikidata.org/wiki/Q29956459