Chemicals and Drugs

Uric Acid

An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.

Chemical Identity

Chemical Information

Molecular Formula
C5H4N4O3
Molecular Weight
168.11 g/mol
CAS Registry No.
69-93-2
IUPAC Name
7,9-dihydro-3H-purine-2,6,8-trione
InChIKey
LEHOTFFKMJEONL-UHFFFAOYSA-N
SMILES
C12=C(NC(=O)N1)NC(=O)NC2=O
MeSH Unique ID
D014527
Source
PubChem CID 1175

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

Loading graph…

Drag nodes to rearrange; hover to trace links; click a node to open its page.

Drug Class

Pharmacological Action

MeSH Record

Synonyms

23 entry terms
  • 2,6,8-Trihydroxypurine
  • Trioxopurine
  • Acid, Uric
  • Ammonium Acid Urate
  • Monosodium Urate
  • Monosodium Urate Monohydrate
  • Potassium Urate
  • Sodium Acid Urate
  • Sodium Acid Urate Monohydrate
  • Sodium Urate
  • Sodium Urate Monohydrate
  • Urate
  • Acid Urate, Ammonium
  • Acid Urate, Sodium
  • Monohydrate, Monosodium Urate
  • Monohydrate, Sodium Urate
  • Urate Monohydrate, Monosodium
  • Urate Monohydrate, Sodium
  • Urate, Ammonium Acid
  • Urate, Monosodium
  • Urate, Potassium
  • Urate, Sodium
  • Urate, Sodium Acid

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Hierarchy

Tree Numbers

  1. D03w.132w.960.877w
  2. D03w.633.100.759.758w.824.877w

AMA Style

References

  1. National Library of Medicine. Uric Acid. Medical Subject Headings (MeSH). 2026. Unique ID D014527. http://id.nlm.nih.gov/mesh/2026/D014527
  2. Uric Acid. In: Wikipedia. https://en.wikipedia.org/wiki/Uric_acid
  3. Uric Acid. In: Wikidata. https://www.wikidata.org/wiki/Q105522
  4. Uric Acid. In: PubChem Compound. CID 1175. https://pubchem.ncbi.nlm.nih.gov/compound/1175