Chemicals and Drugs

UDPglucose-Hexose-1-Phosphate Uridylyltransferase

An enzyme that catalyzes the transfer of UMP from UDPglucose to galactose 1-phosphate, forming UDPgalactose and glucose 1-phosphate. Deficiency in this enzyme is the major cause of GALACTOSEMIA. EC 2.7.7.12.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An enzyme that catalyzes the transfer of UMP from UDPglucose to galactose 1-phosphate, forming UDPgalactose and glucose 1-phosphate. Deficiency in this enzyme is the major cause of GALACTOSEMIA. EC 2.7.7.12.

MeSH Record

Classification

Broader headings

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See Also

MeSH Record

Synonyms

10 entry terms
  • Galactose-1-P-Uridyltransferase
  • Hexosephosphate Uridylyltransferase
  • Phosphogalactose Uridyl Transferase
  • Uridyl Transferase
  • Galactose 1 P Uridyltransferase
  • Transferase, Phosphogalactose Uridyl
  • Transferase, Uridyl
  • Uridyl Transferase, Phosphogalactose
  • Uridylyltransferase, Hexosephosphate
  • Uridylyltransferase, UDPglucose-Hexose-1-Phosphate

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

Indexing Annotation

/defic: consider GALACTOSEMIAS

MeSH Record

History Note

98(75)

MeSH Record

Previous Indexing

  • Galactose (1970-1974)
  • Hexosephosphates (1970-1974)
  • Nucleotidyltransferases (1970-1974)
  • Uridine Diphosphate Sugars (1970-1974)

MeSH Hierarchy

Tree Number

  1. D08.811w.913w.696w.445w.850w

AMA Style

References

  1. National Library of Medicine. UDPglucose-Hexose-1-Phosphate Uridylyltransferase. Medical Subject Headings (MeSH). 2026. Unique ID D006599. http://id.nlm.nih.gov/mesh/2026/D006599
  2. UDPglucose-Hexose-1-Phosphate Uridylyltransferase. In: Wikipedia. https://en.wikipedia.org/wiki/UDP-glucose%E2%80%94hexose-1-phosphate_uridylyltransferase
  3. UDPglucose-Hexose-1-Phosphate Uridylyltransferase. In: Wikidata. https://www.wikidata.org/wiki/Q17141195