Chemicals and Drugs

Tyrosine Phenol-Lyase

An enzyme that catalyzes the cleavage of tyrosine to phenol, pyruvate, and ammonia. It is a pyridoxal phosphate protein. The enzyme also forms pyruvate from D-tyrosine, L-cysteine, S-methyl-L-cysteine, L-serine, and D-serine, although at a slower rate. EC 4.1.99.2.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An enzyme that catalyzes the cleavage of tyrosine to phenol, pyruvate, and ammonia. It is a pyridoxal phosphate protein. The enzyme also forms pyruvate from D-tyrosine, L-cysteine, S-methyl-L-cysteine, L-serine, and D-serine, although at a slower rate. EC 4.1.99.2.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

4 entry terms
  • beta-Tyrosinase
  • Phenol-Lyase, Tyrosine
  • Tyrosine Phenol Lyase
  • beta Tyrosinase

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

91(75); was see under LYASES 1975-90

MeSH Record

Previous Indexing

  • Lyases (1972-1974)
  • Phenols (1974)
  • Tyrosine (1972-1974)

MeSH Hierarchy

Tree Number

AMA Style

References

  1. National Library of Medicine. Tyrosine Phenol-Lyase. Medical Subject Headings (MeSH). 2026. Unique ID D014447. http://id.nlm.nih.gov/mesh/2026/D014447
  2. Tyrosine Phenol-Lyase. In: Wikipedia. https://en.wikipedia.org/wiki/Tyrosine_phenol-lyase
  3. Tyrosine Phenol-Lyase. In: Wikidata. https://www.wikidata.org/wiki/Q7861689