Structured Summary
Abstract
A novel member of the tumor-necrosis factor receptor family that can also mediate HERPES SIMPLEX VIRUS TYPE 1 entry into cells. It has specificity for TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 14 and the homotrimeric form of LYMPHOTOXIN-ALPHA. The receptor is abundantly expressed on T-LYMPHOCYTES and may play a role in regulating lymphocyte activation. Signaling by the activated receptor occurs through its association with TNF RECEPTOR-ASSOCIATED FACTORS.
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Synonyms
7 entry terms
- HVEM Protein
- Herpesvirus Entry Mediator
- HveA Protein
- Receptors, Tumor Necrosis Factor, Member 14
- Tumor Necrosis Factor Receptor Subfamily, Member 14
- Tumor Necrosis Factor Receptor Superfamily, Member 14
- Entry Mediator, Herpesvirus
MeSH Record
Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2007(1997)
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References
- National Library of Medicine. Tumor Necrosis Factor Member 14 Receptors. Medical Subject Headings (MeSH). 2026. Unique ID D053240. http://id.nlm.nih.gov/mesh/2026/D053240
- Tumor Necrosis Factor Member 14 Receptors. In: Wikidata. https://www.wikidata.org/wiki/Q21135813