Chemicals and Drugs

Troponin C

A TROPONIN complex subunit that binds calcium and help regulate calcium-dependent muscle contraction. There are two troponin C subtypes: troponin C1 and C2. Troponin C1 is skeletal and cardiac type whereas troponin C2 is skeletal type. Troponin C1 is a BIOMARKER for damaged or injured CARDIAC MYOCYTES and mutations in troponin C1 gene are associated with FAMILIAL HYPERTROPHIC CARDIOMYOPATHY.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A TROPONIN complex subunit that binds calcium and help regulate calcium-dependent muscle contraction. There are two troponin C subtypes: troponin C1 and C2. Troponin C1 is skeletal and cardiac type whereas troponin C2 is skeletal type. Troponin C1 is a BIOMARKER for damaged or injured CARDIAC MYOCYTES and mutations in troponin C1 gene are associated with FAMILIAL HYPERTROPHIC CARDIOMYOPATHY.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

3 entry terms
  • Troponin-C
  • Troponin C1
  • Troponin C2

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

Indexing Annotation

TROPONIN I & TROPONIN T are also available

MeSH Record

History Note

97; was TROPONIN C (NM) 1975-96

MeSH Record

Previous Indexing

  • Muscle Proteins (1975-1979)
  • Troponin (1980-1996)

MeSH Hierarchy

Tree Numbers

  1. D05.500w.945w.900w
  2. D05.750w.078w.730.825w.900w
  3. D12.776w.157w.125w.900w
  4. D12.776w.210.500.910w.900w
  5. D12.776w.220.525.825w.900w

AMA Style

References

  1. National Library of Medicine. Troponin C. Medical Subject Headings (MeSH). 2026. Unique ID D019209. http://id.nlm.nih.gov/mesh/2026/D019209
  2. Troponin C. In: Wikipedia. https://en.wikipedia.org/wiki/Troponin_C
  3. Troponin C. In: Wikidata. https://www.wikidata.org/wiki/Q4383200