Chemicals and Drugs

Tropisetron

An indole derivative and 5-HT3 RECEPTOR antagonist that is used for the prevention of nausea and vomiting.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An indole derivative and 5-HT3 RECEPTOR antagonist that is used for the prevention of nausea and vomiting.

Chemical Identity

Chemical Information

Molecular Formula
C17H20N2O2
Molecular Weight
284.35 g/mol
IUPAC Name
[(1S,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] 1H-indole-3-carboxylate
InChIKey
ZNRGQMMCGHDTEI-RYUDHWBXSA-N
SMILES
CN1[C@H]2CC[C@H]1CC(C2)OC(=O)C3=CNC4=CC=CC=C43
MeSH Unique ID
D000077526
Source
PubChem CID 72165

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

10 entry terms
  • (3 alpha-Tropanyl)-1H-indole-3-carboxylic Acid Ester
  • ICS 205-930
  • ICS-205-930
  • ICS-205930
  • Indole-3-carboxylic Acid Tropine Ester
  • Navoban
  • Tropisetron Hydrochloride
  • ICS 205 930
  • ICS 205930
  • Indole 3 carboxylic Acid Tropine Ester

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

2019 (1985)

MeSH Hierarchy

Tree Number

AMA Style

References

  1. National Library of Medicine. Tropisetron. Medical Subject Headings (MeSH). 2026. Unique ID D000077526. http://id.nlm.nih.gov/mesh/2026/D000077526
  2. Tropisetron. In: Wikipedia. https://en.wikipedia.org/wiki/Tropisetron
  3. Tropisetron. In: Wikidata. https://www.wikidata.org/wiki/Q29428
  4. Tropisetron. In: PubChem Compound. CID 72165. https://pubchem.ncbi.nlm.nih.gov/compound/72165