Diseases

Tropical Spastic Paraparesis

A subacute paralytic myeloneuropathy occurring endemically in tropical areas such as the Caribbean, Colombia, India, and Africa, as well as in the southwestern region of Japan; associated with infection by HUMAN T-CELL LEUKEMIA VIRUS I. Clinical manifestations include a slowly progressive spastic weakness of the legs, increased reflexes, Babinski signs, incontinence, and loss of vibratory and position sensation. On pathologic examination inflammatory, demyelination, and necrotic lesions may be found in the spinal cord. (Adams et al., Principles of Neurology, 6th ed, p1239)

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A subacute paralytic myeloneuropathy occurring endemically in tropical areas such as the Caribbean, Colombia, India, and Africa, as well as in the southwestern region of Japan; associated with infection by HUMAN T-CELL LEUKEMIA VIRUS I. Clinical manifestations include a slowly progressive spastic weakness of the legs, increased reflexes, Babinski signs, incontinence, and loss of vibratory and position sensation. On pathologic examination inflammatory, demyelination, and necrotic lesions may be found in the spinal cord. (Adams et al., Principles of Neurology, 6th ed, p1239)

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MeSH Record

Synonyms

31 entry terms
  • Familial Spastic Paraparesis, Htlv-1-Associated
  • HTLV I Associated Myelopathies
  • HTLV-I-Associated Myelopathy
  • HTLV-I-Associated Myelopathy-Tropical Spastic Paraparesis
  • Human T-Lymphotropic Virus Type 1 Associated Myelopathy
  • Myelopathies, HTLV I Associated
  • Myelopathy, Htlv-1-Associated
  • Myelopathy, Human T-Lymphotropic Virus Type 1 Associated
  • Paraparesis, Tropical Spastic
  • Paraplegia, Tropical Spastic
  • Familial Spastic Paraparesis, Htlv 1 Associated
  • HTLV I Associated Myelopathy
  • HTLV I Associated Myelopathy Tropical Spastic Paraparesis
  • HTLV-I-Associated Myelopathies
  • Htlv-1-Associated Myelopathies
  • Htlv-1-Associated Myelopathy
  • Human T Lymphotropic Virus Type 1 Associated Myelopathy
  • Myelopathies, HTLV-I-Associated
  • Myelopathies, Htlv-1-Associated
  • Myelopathy, HTLV-I-Associated
  • Myelopathy, Htlv 1 Associated
  • Myelopathy, Human T Lymphotropic Virus Type 1 Associated
  • Parapareses, Tropical Spastic
  • Paraplegias, Tropical Spastic
  • Spastic Parapareses, Tropical
  • Spastic Paraparesis, Tropical
  • Spastic Paraplegia, Tropical
  • Spastic Paraplegias, Tropical
  • Tropical Spastic Parapareses
  • Tropical Spastic Paraplegia
  • Tropical Spastic Paraplegias

MeSH Record

Aspects Covered

36 allowable subheadings

Indexed with the subheadings blood, cerebrospinal fluid, chemically induced, classification, complications, congenital, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, transmission, urine, veterinary, virology.

MeSH Record

History Note

1989

MeSH Record

Previous Indexing

  • HTLV Infections (1987-1988)
  • Human T-Cell Leukemia Virus (1985-1988)
  • Paralysis (1984-1988)
  • Paraplegia (1983-1988)
  • Retrovirus Infections (1985-1986)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Tropical Spastic Paraparesis. Medical Subject Headings (MeSH). 2026. Unique ID D015493. http://id.nlm.nih.gov/mesh/2026/D015493
  2. Tropical Spastic Paraparesis. In: Wikipedia. https://en.wikipedia.org/wiki/Tropical_spastic_paraparesis
  3. Tropical Spastic Paraparesis. In: Wikidata. https://www.wikidata.org/wiki/Q1476361