Structured Summary
Abstract
An organic amine proton acceptor. It is used in the synthesis of surface-active agents and pharmaceuticals; as an emulsifying agent for cosmetic creams and lotions, mineral oil and paraffin wax emulsions, as a biological buffer, and used as an alkalizer. (From Merck, 11th ed; Martindale, The Extra Pharmacopoeia, 30th ed, p1424)
Chemical Identity
Chemical Information
- Molecular Formula
- C4H11NO3
- Molecular Weight
- 121.14 g/mol
- CAS Registry No.
- 77-86-1
- IUPAC Name
- 2-amino-2-(hydroxymethyl)propane-1,3-diol
- InChIKey
- LENZDBCJOHFCAS-UHFFFAOYSA-N
- SMILES
- C(C(CO)(CO)N)O
- MeSH Unique ID
- D014325
- Source
- PubChem CID 6503
MeSH Record
Classification
Broader headings
Related Concepts
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
8 entry terms
- Tri(hydroxymethyl)aminomethane
- Tris Buffer
- Tris(hydroxymethyl)aminomethane
- Trisamine
- Trometamol
- Tris-Magnesium(II)-Potassium Chloride Buffer
- Tris-Mg(II)-KCl Buffer
- Trizma
MeSH Record
Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
65
MeSH Hierarchy
Tree Number
AMA Style
References
- National Library of Medicine. Tromethamine. Medical Subject Headings (MeSH). 2026. Unique ID D014325. http://id.nlm.nih.gov/mesh/2026/D014325
- Tromethamine. In: Wikipedia. https://en.wikipedia.org/wiki/Tris
- Tromethamine. In: Wikidata. https://www.wikidata.org/wiki/Q413961
- Tromethamine. In: PubChem Compound. CID 6503. https://pubchem.ncbi.nlm.nih.gov/compound/6503