Chemicals and Drugs

Trichothecenes

Usually 12,13-epoxytrichothecenes, produced by Fusaria, Stachybotrys, Trichoderma and other fungi, and some higher plants. They may contaminate food or feed grains, induce emesis and hemorrhage in lungs and brain, and damage bone marrow due to protein and DNA synthesis inhibition.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Usually 12,13-epoxytrichothecenes, produced by Fusaria, Stachybotrys, Trichoderma and other fungi, and some higher plants. They may contaminate food or feed grains, induce emesis and hemorrhage in lungs and brain, and damage bone marrow due to protein and DNA synthesis inhibition.

MeSH Record

Classification

Related Concepts

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

3 entry terms
  • Epoxytrichothecenes
  • Trichothecene Epoxides
  • Epoxides, Trichothecene

MeSH Record

Aspects Covered

24 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

91(81); was see under SESQUITERPENES 1981-90; was EPOXYTRICHOTHECENES see under SESQUITERPENES 1975-80

MeSH Record

Previous Indexing

  • Benzoxepins (1968-1974)
  • Ethers, Cyclic (1966-1974)
  • Sesquiterpenes (1974)
  • Terpenes (1966-1973)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Trichothecenes. Medical Subject Headings (MeSH). 2026. Unique ID D014255. http://id.nlm.nih.gov/mesh/2026/D014255
  2. Trichothecenes. In: Wikipedia. https://en.wikipedia.org/wiki/Trichothecene
  3. Trichothecenes. In: Wikidata. https://www.wikidata.org/wiki/Q257954