Chemicals and Drugs

Trichloroepoxypropane

A potent epoxide hydrase and aryl hydrocarbon hydroxylase inhibitor. It enhances the tumor-initiating ability of certain carcinogens.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A potent epoxide hydrase and aryl hydrocarbon hydroxylase inhibitor. It enhances the tumor-initiating ability of certain carcinogens.

Chemical Identity

Chemical Information

Molecular Formula
C3H3Cl3O
Molecular Weight
161.41 g/mol
CAS Registry No.
3083-23-6
IUPAC Name
2-(trichloromethyl)oxirane
InChIKey
VFEXYZINKMLLAK-UHFFFAOYSA-N
SMILES
C1C(O1)C(Cl)(Cl)Cl
MeSH Unique ID
D014239
Source
PubChem CID 18321

MeSH Record

Classification

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

8 entry terms
  • 1,1,1-Trichloropropene-2,3-oxide
  • 1,2-Epoxy-3,3,3-Trichloropropane
  • Trichloropropane Oxide
  • Trichloropropene Oxide
  • Trichloropropylene Oxide
  • Oxide, Trichloropropane
  • Oxide, Trichloropropene
  • Oxide, Trichloropropylene

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

91(80); was see under HYDROCARBONS, CHLORINATED 1980-90

MeSH Record

Previous Indexing

  • Epoxy Compounds (1975-1979)
  • Ethers, Cyclic (1966-1974)
  • Hydrocarbons, Chlorinated (1974-1979)
  • Hydrocarbons, Halogenated (1966-1973)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Trichloroepoxypropane. Medical Subject Headings (MeSH). 2026. Unique ID D014239. http://id.nlm.nih.gov/mesh/2026/D014239
  2. Trichloroepoxypropane. In: Wikidata. https://www.wikidata.org/wiki/Q27280849
  3. Trichloroepoxypropane. In: PubChem Compound. CID 18321. https://pubchem.ncbi.nlm.nih.gov/compound/18321