Chemicals and Drugs

Trefoil Factor-3

A 59 amino acid (6.6 kDa) trefoil factor that contains a single trefoil domain. It is expressed in all tissues with MUCOUS MEMBRANES, including GOBLET CELLS of the SMALL INTESTINE and LARGE INTESTINE. It associates with MUCIN-2 in the small intestine and may regulate epithelial CELL MIGRATION and WOUND HEALING.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A 59 amino acid (6.6 kDa) trefoil factor that contains a single trefoil domain. It is expressed in all tissues with MUCOUS MEMBRANES, including GOBLET CELLS of the SMALL INTESTINE and LARGE INTESTINE. It associates with MUCIN-2 in the small intestine and may regulate epithelial CELL MIGRATION and WOUND HEALING.

MeSH Record

Classification

Broader headings

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MeSH Record

Synonyms

5 entry terms
  • Intestinal Trefoil Factor
  • TFF3 Peptide
  • TFF3 Protein
  • Trefoil Factor 3
  • Trefoil Factor, Intestinal

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

2017 (1992)

MeSH Hierarchy

Tree Number

  1. D12.644w.937.875

AMA Style

References

  1. National Library of Medicine. Trefoil Factor-3. Medical Subject Headings (MeSH). 2026. Unique ID D000071165. http://id.nlm.nih.gov/mesh/2026/D000071165
  2. Trefoil Factor-3. In: Wikidata. https://www.wikidata.org/wiki/Q7837795