Psychiatry and Psychology

Treatment-Resistant Depressive Disorder

Failure to respond to two or more trials of antidepressant monotherapy or failure to respond to four or more trials of different antidepressant therapies. (Campbell's Psychiatric Dictionary, 9th ed.)

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Failure to respond to two or more trials of antidepressant monotherapy or failure to respond to four or more trials of different antidepressant therapies. (Campbell's Psychiatric Dictionary, 9th ed.)

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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MeSH Record

Synonyms

21 entry terms
  • Depressive Disorder, Treatment-Resistant
  • Refractory Depression
  • Therapy-Resistant Depression
  • Treatment Resistant Depression
  • Depression, Refractory
  • Depression, Therapy-Resistant
  • Depression, Treatment Resistant
  • Depressions, Refractory
  • Depressions, Therapy-Resistant
  • Depressions, Treatment Resistant
  • Depressive Disorder, Treatment Resistant
  • Depressive Disorders, Treatment-Resistant
  • Disorder, Treatment-Resistant Depressive
  • Disorders, Treatment-Resistant Depressive
  • Refractory Depressions
  • Resistant Depression, Treatment
  • Resistant Depressions, Treatment
  • Therapy Resistant Depression
  • Therapy-Resistant Depressions
  • Treatment Resistant Depressions
  • Treatment-Resistant Depressive Disorders

MeSH Record

Aspects Covered

31 allowable subheadings

Indexed with the subheadings blood, cerebrospinal fluid, chemically induced, classification, complications, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, rehabilitation, surgery, therapy, urine, virology.

MeSH Record

History Note

2012

MeSH Record

Previous Indexing

  • Depressive Disorder (1981-2011)

MeSH Hierarchy

Tree Number

  1. F03w.600w.300.388w

AMA Style

References

  1. National Library of Medicine. Treatment-Resistant Depressive Disorder. Medical Subject Headings (MeSH). 2026. Unique ID D061218. http://id.nlm.nih.gov/mesh/2026/D061218
  2. Treatment-Resistant Depressive Disorder. In: Wikipedia. https://en.wikipedia.org/wiki/Treatment-resistant_depression
  3. Treatment-Resistant Depressive Disorder. In: Wikidata. https://www.wikidata.org/wiki/Q7836891