Chemicals and Drugs

Transposases

Enzymes that recombine DNA segments by a process which involves the formation of a synapse between two DNA helices, the cleavage of single strands from each DNA helix and the ligation of a DNA strand from one DNA helix to the other. The resulting DNA structure is called a Holliday junction which can be resolved by DNA REPLICATION or by HOLLIDAY JUNCTION RESOLVASES.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Enzymes that recombine DNA segments by a process which involves the formation of a synapse between two DNA helices, the cleavage of single strands from each DNA helix and the ligation of a DNA strand from one DNA helix to the other. The resulting DNA structure is called a Holliday junction which can be resolved by DNA REPLICATION or by HOLLIDAY JUNCTION RESOLVASES.

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Synonyms

1 entry terms
  • Transposase

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Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2004(1998); use TRANSPOSASE (NM) 1981-1997

MeSH Record

Previous Indexing

  • DNA Nucleotidyltransferases (1996-1997)
  • Nucleotidyltransferases (1981-1995)

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AMA Style

References

  1. National Library of Medicine. Transposases. Medical Subject Headings (MeSH). 2026. Unique ID D019895. http://id.nlm.nih.gov/mesh/2026/D019895
  2. Transposases. In: Wikipedia. https://en.wikipedia.org/wiki/Transposase
  3. Transposases. In: Wikidata. https://www.wikidata.org/wiki/Q410629