Structured Summary
Abstract
A TGF-beta subtype that plays role in regulating epithelial-mesenchymal interaction during embryonic development. It is synthesized as a precursor molecule that is cleaved to form mature TGF-beta3 and TGF-beta3 latency-associated peptide. The association of the cleavage products results in the formation a latent protein which must be activated to bind its receptor.
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Broader headings
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MeSH Record
Synonyms
10 entry terms
- TGF-beta-3
- TGF-beta3
- TGFB3
- TGF beta 3
- TGF beta3
- TGF-beta3 Latency-Associated Protein
- TGF-beta3LAP
- Transforming Growth Factor beta 3 Latency Associated Peptide
- Latency-Associated Protein, TGF-beta3
- TGF beta3 Latency Associated Protein
MeSH Record
Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2007(2000)
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AMA Style
References
- National Library of Medicine. Transforming Growth Factor beta3. Medical Subject Headings (MeSH). 2026. Unique ID D053782. http://id.nlm.nih.gov/mesh/2026/D053782
- Transforming Growth Factor beta3. In: Wikidata. https://www.wikidata.org/wiki/Q24773431