Phenomena and Processes

Trained Immunity

Ability of the INNATE IMMUNITY system to form IMMUNOLOGIC MEMORY and provide enhanced defense against subsequent secondary infections. In trained immunity, long-term adaptation of innate immune cells occurs through EPIGENETIC PROCESSES and metabolic CELLULAR REPROGRAMMING to form long term immunologic memory.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Ability of the INNATE IMMUNITY system to form IMMUNOLOGIC MEMORY and provide enhanced defense against subsequent secondary infections. In trained immunity, long-term adaptation of innate immune cells occurs through EPIGENETIC PROCESSES and metabolic CELLULAR REPROGRAMMING to form long term immunologic memory.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

15 entry terms
  • Innate Immune Memory
  • Innate Trained Immunity
  • Trained Innate Immunity
  • Immune Memories, Innate
  • Immune Memory, Innate
  • Immunity, Trained
  • Immunity, Trained Innate
  • Innate Immune Memories
  • Innate Immunity, Trained
  • Innate Trained Immunities
  • Memories, Innate Immune
  • Memory, Innate Immune
  • Trained Immunities
  • Trained Immunity, Innate
  • Trained Innate Immunities

MeSH Record

Aspects Covered

5 allowable subheadings

Indexed with the subheadings drug effects, genetics, immunology, physiology, radiation effects.

MeSH Record

History Note

2023

MeSH Record

Previous Indexing

  • Immunity, Innate (2011-2022)

MeSH Hierarchy

Tree Number

  1. G12.450w.564w.904w

AMA Style

References

  1. National Library of Medicine. Trained Immunity. Medical Subject Headings (MeSH). 2026. Unique ID D000094384. http://id.nlm.nih.gov/mesh/2026/D000094384
  2. Trained Immunity. In: Wikipedia. https://en.wikipedia.org/wiki/Trained_immunity
  3. Trained Immunity. In: Wikidata. https://www.wikidata.org/wiki/Q66809844