Structured Summary
Abstract
A sulfamate-substituted fructose analog that was originally identified as a hypoglycemic agent. It is used for the treatment of EPILEPSY and MIGRAINE DISORDERS, and may also promote weight loss.
Chemical Identity
Chemical Information
- Molecular Formula
- C12H21NO8S
- Molecular Weight
- 339.36 g/mol
- CAS Registry No.
- 97240-79-4
- IUPAC Name
- [(1R,2S,6S,9R)-4,4,11,11-tetramethyl-3,5,7,10,12-pentaoxatricyclo[7.3.0.02,6]dodecan-6-yl]methyl sulfamate
- InChIKey
- KJADKKWYZYXHBB-XBWDGYHZSA-N
- SMILES
- CC1(O[C@@H]2CO[C@@]3([C@H]([C@@H]2O1)OC(O3)(C)C)COS(=O)(=O)N)C
- MeSH Unique ID
- D000077236
- Source
- PubChem CID 5284627
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
7 entry terms
- 2,3-4,5-bis-O-(1-methylethylidene)-beta-D-fructopyranose sulfamate
- Epitomax
- McN 4853
- McN-4853
- Topamax
- USL255
- McN4853
MeSH Record
Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
2019 (1987)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Topiramate. Medical Subject Headings (MeSH). 2026. Unique ID D000077236. http://id.nlm.nih.gov/mesh/2026/D000077236
- Topiramate. In: Wikipedia. https://en.wikipedia.org/wiki/Topiramate
- Topiramate. In: Wikidata. https://www.wikidata.org/wiki/Q221174
- Topiramate. In: PubChem Compound. CID 5284627. https://pubchem.ncbi.nlm.nih.gov/compound/5284627