Chemicals and Drugs

Tocainide

An antiarrhythmic agent which exerts a potential- and frequency-dependent block of SODIUM CHANNELS.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An antiarrhythmic agent which exerts a potential- and frequency-dependent block of SODIUM CHANNELS.

Chemical Identity

Chemical Information

Molecular Formula
C11H16N2O
Molecular Weight
192.26 g/mol
CAS Registry No.
41708-72-9
IUPAC Name
2-amino-N-(2,6-dimethylphenyl)propanamide
InChIKey
BUJAGSGYPOAWEI-UHFFFAOYSA-N
SMILES
CC1=C(C(=CC=C1)C)NC(=O)C(C)N
MeSH Unique ID
D016677
Source
PubChem CID 38945

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

15 entry terms
  • Tocainide Hydrochloride
  • Tocainide Monohdyrochloride, (R)-Isomer
  • Tocainide Monohydrobromide, (R)-Isomer
  • Tocainide Monohydrochloride
  • Tocainide Monohydrochloride, (+-)-Isomer
  • Tocainide Monohydrochloride, (S)-Isomer
  • Tocainide, (+-)-Isomer
  • Tocainide, (R)-Isomer
  • Tocainide, (S)-Isomer
  • Tonocard
  • W-36095
  • Xylotocan
  • Hydrochloride, Tocainide
  • W 36095
  • W36095

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

92; was TOCAINIDE (NM) 1974-91

MeSH Record

Previous Indexing

  • Anilides (1974-1981)
  • Anti-Arrhythmia Agents (1966-1991)
  • Lidocaine/analogs & derivatives (1982-1991)

MeSH Hierarchy

Tree Numbers

  1. D02w.065w.199w.920w
  2. D02w.092w.146.113w.920w

AMA Style

References

  1. National Library of Medicine. Tocainide. Medical Subject Headings (MeSH). 2026. Unique ID D016677. http://id.nlm.nih.gov/mesh/2026/D016677
  2. Tocainide. In: Wikipedia. https://en.wikipedia.org/wiki/Tocainide
  3. Tocainide. In: Wikidata. https://www.wikidata.org/wiki/Q757058
  4. Tocainide. In: PubChem Compound. CID 38945. https://pubchem.ncbi.nlm.nih.gov/compound/38945