Chemicals and Drugs

Tissue Kallikreins

A family of trypsin-like SERINE ENDOPEPTIDASES that are expressed in a variety of cell types including human prostate epithelial cells. They are formed from tissue prokallikrein by action with TRYPSIN. They are highly similar to PROSTATE-SPECIFIC ANTIGEN.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A family of trypsin-like SERINE ENDOPEPTIDASES that are expressed in a variety of cell types including human prostate epithelial cells. They are formed from tissue prokallikrein by action with TRYPSIN. They are highly similar to PROSTATE-SPECIFIC ANTIGEN.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

26 entry terms
  • Glandular Kallikrein
  • Human Glandular Kallikreins
  • Tissue Kallikrein
  • Glandular Kallikreins, Human
  • Kallikrein, Glandular
  • Kallikrein, Tissue
  • Kallikreins, Human Glandular
  • Kallikreins, Tissue
  • Glandular Kallikrein-1
  • Human Glandular Kallikrein 1
  • Human Glandular Kallikrein 2
  • Kallikrein 1
  • Kallikrein 2
  • Pancreatic Kallikrein
  • Prostate Specific Kallikrein
  • Urinary Kallikrein
  • hK1 Kallikrein
  • hK2 Kallikrein
  • Glandular Kallikrein 1
  • Kallikrein, Pancreatic
  • Kallikrein, Prostate Specific
  • Kallikrein, Urinary
  • Kallikrein, hK1
  • Kallikrein, hK2
  • Kallikrein-1, Glandular
  • Specific Kallikrein, Prostate

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

Indexing Annotation

do not confuse PROSTATE SPECIFIC KALLIKREIN with PROSTATE SPECIFIC ANTIGEN

MeSH Record

History Note

2000; use TISSUE KALLIKREIN (NM) 1983-1999

MeSH Record

Previous Indexing

  • Endopeptidases (1982-1983)
  • Kallikreins (1983-1999)

MeSH Hierarchy

Tree Numbers

  1. D08.811w.277w.656w.300w.760.442w.875
  2. D08.811w.277w.656w.959w.350.442w.875
  3. D23.101w.140.870

AMA Style

References

  1. National Library of Medicine. Tissue Kallikreins. Medical Subject Headings (MeSH). 2026. Unique ID D020840. http://id.nlm.nih.gov/mesh/2026/D020840
  2. Tissue Kallikreins. In: Wikidata. https://www.wikidata.org/wiki/Q77837338