Chemicals and Drugs

Tilorone

An antiviral agent used as its hydrochloride. It is the first recognized synthetic, low-molecular-weight compound that is an orally active interferon inducer, and is also reported to have antineoplastic and anti-inflammatory actions.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An antiviral agent used as its hydrochloride. It is the first recognized synthetic, low-molecular-weight compound that is an orally active interferon inducer, and is also reported to have antineoplastic and anti-inflammatory actions.

Chemical Identity

Chemical Information

Molecular Formula
C25H34N2O3
Molecular Weight
410.5 g/mol
CAS Registry No.
27591-97-5
IUPAC Name
2,7-bis[2-(diethylamino)ethoxy]fluoren-9-one
InChIKey
MPMFCABZENCRHV-UHFFFAOYSA-N
SMILES
CCN(CC)CCOC1=CC2=C(C=C1)C3=C(C2=O)C=C(C=C3)OCCN(CC)CC
MeSH Unique ID
D013994
Source
PubChem CID 5475

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

7 entry terms
  • Bis-DEAE-Fluorenone
  • Bis DEAE Fluorenone
  • Amiksin
  • Amixin
  • Amyxin
  • Tilorone Hydrochloride
  • Hydrochloride, Tilorone

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

91(75); was see under FLUORENES 1975-90; AMYXIN was AMYXIN (NM) 1988-91

MeSH Record

Previous Indexing

  • Diethylamines (1974)
  • Fluorenes (1971-1974)

MeSH Hierarchy

Tree Numbers

  1. D02w.455w.426w.559w.847w.389.850w
  2. D04w.615w.389.850w

AMA Style

References

  1. National Library of Medicine. Tilorone. Medical Subject Headings (MeSH). 2026. Unique ID D013994. http://id.nlm.nih.gov/mesh/2026/D013994
  2. Tilorone. In: Wikipedia. https://en.wikipedia.org/wiki/Tilorone
  3. Tilorone. In: Wikidata. https://www.wikidata.org/wiki/Q2028068
  4. Tilorone. In: PubChem Compound. CID 5475. https://pubchem.ncbi.nlm.nih.gov/compound/5475