Chemicals and Drugs

Tiapamil Hydrochloride

A phenylethylamine derivative that acts as a calcium antagonist showing hemodynamic effects in patients with acute myocardial infarction.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A phenylethylamine derivative that acts as a calcium antagonist showing hemodynamic effects in patients with acute myocardial infarction.

Chemical Identity

Chemical Information

Molecular Formula
C26H40ClNO9S2
Molecular Weight
610.2 g/mol
CAS Registry No.
87434-83-1
IUPAC Name
N-[2-(3,4-dimethoxyphenyl)ethyl]-3-[2-(3,4-dimethoxyphenyl)-1,1,3,3-tetraoxo-1,3-dithian-2-yl]-N-methylpropan-1-amine;hydrate;hydrochloride
InChIKey
QRLOEYBBNMCMIM-UHFFFAOYSA-N
SMILES
CN(CCCC1(S(=O)(=O)CCCS1(=O)=O)C2=CC(=C(C=C2)OC)OC)CCC3=CC(=C(C=C3)OC)OC.O.Cl
MeSH Unique ID
D013976
Source
PubChem CID 23621171

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

9 entry terms
  • N-(3,4-dimethoxyphenethyl)-2-(3,4-dimethoxyphenyl)-N-methyl-m-dithian-2-propylamin-1,1,3,3-tetroxide hydrochloride
  • Hydrochloride, Tiapamil
  • Dimeditiapramine
  • Dimeditiapramine Hydrochloride
  • Ro 11-1781
  • Tiapamil
  • Hydrochloride, Dimeditiapramine
  • Ro 11 1781
  • Ro 111781

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

2012; DIMEDITIAPRAMINE was indexed under PROLAMINES 1982-2011, under HETEROCYCLIC COMPOUNDS, CALCIUM, and PHENYL ETHERS 1977-1981

MeSH Record

Previous Indexing

  • Amides (1966-1972)
  • Benzamides (1973-1979)
  • Benzoates (1966-1972)

MeSH Hierarchy

Tree Numbers

  1. D02w.092w.471.683w.943
  2. D02w.355w.726.825

AMA Style

References

  1. National Library of Medicine. Tiapamil Hydrochloride. Medical Subject Headings (MeSH). 2026. Unique ID D013976. http://id.nlm.nih.gov/mesh/2026/D013976
  2. Tiapamil Hydrochloride. In: Wikidata. https://www.wikidata.org/wiki/Q27291647
  3. Tiapamil Hydrochloride. In: PubChem Compound. CID 23621171. https://pubchem.ncbi.nlm.nih.gov/compound/23621171