Diseases

Thrombocytopenic Idiopathic Purpura

Thrombocytopenia occurring in the absence of toxic exposure or a disease associated with decreased platelets. It is mediated by immune mechanisms, in most cases IMMUNOGLOBULIN G autoantibodies which attach to platelets and subsequently undergo destruction by macrophages. The disease is seen in acute (affecting children) and chronic (adult) forms.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Thrombocytopenia occurring in the absence of toxic exposure or a disease associated with decreased platelets. It is mediated by immune mechanisms, in most cases IMMUNOGLOBULIN G autoantibodies which attach to platelets and subsequently undergo destruction by macrophages. The disease is seen in acute (affecting children) and chronic (adult) forms.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

32 entry terms
  • Autoimmune Thrombocytopenia
  • Autoimmune Thrombocytopenic Purpura
  • Idiopathic Thrombocytopenic Purpura
  • Immune Thrombocytopenia
  • Immune Thrombocytopenic Purpura
  • Purpura, Thrombocytopenic, Autoimmune
  • Purpura, Thrombocytopenic, Idiopathic
  • Thrombocytopenic Purpura, Autoimmune
  • Werlhof Disease
  • Werlhof's Disease
  • Autoimmune Thrombocytopenias
  • Autoimmune Thrombocytopenic Purpuras
  • Disease, Werlhof
  • Disease, Werlhof's
  • Idiopathic Thrombocytopenic Purpuras
  • Immune Thrombocytopenias
  • Immune Thrombocytopenic Purpuras
  • Purpura, Autoimmune Thrombocytopenic
  • Purpura, Idiopathic Thrombocytopenic
  • Purpura, Immune Thrombocytopenic
  • Purpuras, Autoimmune Thrombocytopenic
  • Purpuras, Idiopathic Thrombocytopenic
  • Purpuras, Immune Thrombocytopenic
  • Thrombocytopenia, Autoimmune
  • Thrombocytopenia, Immune
  • Thrombocytopenias, Autoimmune
  • Thrombocytopenias, Immune
  • Thrombocytopenic Purpura, Idiopathic
  • Thrombocytopenic Purpura, Immune
  • Thrombocytopenic Purpuras, Idiopathic
  • Thrombocytopenic Purpuras, Immune
  • Werlhofs Disease

MeSH Record

Aspects Covered

35 allowable subheadings

Indexed with the subheadings blood, cerebrospinal fluid, chemically induced, classification, complications, congenital, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, urine, veterinary, virology.

MeSH Record

History Note

1992; for WERLHOF'S DISEASE use PURPURA, THROMBOCYTOPENIC 1975-1991

MeSH Record

Previous Indexing

  • Purpura, Thrombocytopenic (1966-1991)

MeSH Hierarchy

Tree Numbers

  1. C15.378w.100w.802w.687w.600w
  2. C15.378w.140.855w.925w.750w.600w
  3. C15.378w.243w.937w.925w.750w.600w
  4. C15.378w.463w.740w
  5. C20w.111w.759w
  6. C20w.841w.600w
  7. C23.550.414w.950w.687w.600w
  8. C23.888w.885.687w.687w.600w

MeSH Record

NLM Classification

WH 322

AMA Style

References

  1. National Library of Medicine. Thrombocytopenic Idiopathic Purpura. Medical Subject Headings (MeSH). 2026. Unique ID D016553. http://id.nlm.nih.gov/mesh/2026/D016553
  2. Thrombocytopenic Idiopathic Purpura. In: Wikipedia. https://en.wikipedia.org/wiki/Immune_thrombocytopenic_purpura
  3. Thrombocytopenic Idiopathic Purpura. In: Wikidata. https://www.wikidata.org/wiki/Q638729