Structured Summary
Abstract
A dithiocarbamate chemical, used commercially in the rubber processing industry and as a fungicide. In vivo studies indicate that it inactivates the enzyme GLUTATHIONE REDUCTASE. It has mutagenic activity and may induce chromosomal aberrations.
Chemical Identity
Chemical Information
- Molecular Formula
- C6H12N2S4
- Molecular Weight
- 240.4 g/mol
- CAS Registry No.
- 137-26-8
- IUPAC Name
- dimethylcarbamothioylsulfanyl N,N-dimethylcarbamodithioate
- InChIKey
- KUAZQDVKQLNFPE-UHFFFAOYSA-N
- SMILES
- CN(C)C(=S)SSC(=S)N(C)C
- MeSH Unique ID
- D013893
- Source
- PubChem CID 5455
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
10 entry terms
- TMT Disulfide
- TMTD
- Tetramethylthiuram Disulfide
- Thiuram
- Disulfide, TMT
- Disulfide, Tetramethylthiuram
- Bacteriostat
- Nobecutan
- Sadoplon 75
- Thiuram D
MeSH Record
Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
91(66); was see under THIOCARBAMATES 1966-90
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Thiram. Medical Subject Headings (MeSH). 2026. Unique ID D013893. http://id.nlm.nih.gov/mesh/2026/D013893
- Thiram. In: Wikipedia. https://en.wikipedia.org/wiki/Thiram
- Thiram. In: Wikidata. https://www.wikidata.org/wiki/Q416572
- Thiram. In: PubChem Compound. CID 5455. https://pubchem.ncbi.nlm.nih.gov/compound/5455