Chemicals and Drugs

Thiothixene

A thioxanthine used as an antipsychotic agent. Its effects are similar to the phenothiazine antipsychotics.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A thioxanthine used as an antipsychotic agent. Its effects are similar to the phenothiazine antipsychotics.

Chemical Identity

Chemical Information

Molecular Formula
C23H29N3O2S2
Molecular Weight
443.6 g/mol
CAS Registry No.
5591-45-7
IUPAC Name
(9Z)-N,N-dimethyl-9-[3-(4-methylpiperazin-1-yl)propylidene]thioxanthene-2-sulfonamide
InChIKey
GFBKORZTTCHDGY-UWVJOHFNSA-N
SMILES
CN1CCN(CC1)CC/C=C\2/C3=CC=CC=C3SC4=C2C=C(C=C4)S(=O)(=O)N(C)C
MeSH Unique ID
D013888
Source
PubChem CID 941651

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

2 entry terms
  • Tiotixene
  • Navane

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

73(70)

MeSH Record

Previous Indexing

  • Tranquilizing Agents (1966-1969)
  • Xanthenes (1966-1969)

MeSH Hierarchy

Tree Numbers

MeSH Record

NLM Classification

QV 77.9

AMA Style

References

  1. National Library of Medicine. Thiothixene. Medical Subject Headings (MeSH). 2026. Unique ID D013888. http://id.nlm.nih.gov/mesh/2026/D013888
  2. Thiothixene. In: Wikipedia. https://en.wikipedia.org/wiki/Tiotixene
  3. Thiothixene. In: Wikidata. https://www.wikidata.org/wiki/Q2608288
  4. Thiothixene. In: PubChem Compound. CID 941651. https://pubchem.ncbi.nlm.nih.gov/compound/941651