Chemicals and Drugs

Thioctic Acid

An octanoic acid bridged with two sulfurs so that it is sometimes also called a pentanoic acid in some naming schemes. It is biosynthesized by cleavage of LINOLEIC ACID and is a coenzyme of oxoglutarate dehydrogenase (KETOGLUTARATE DEHYDROGENASE COMPLEX). It is used in DIETARY SUPPLEMENTS.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An octanoic acid bridged with two sulfurs so that it is sometimes also called a pentanoic acid in some naming schemes. It is biosynthesized by cleavage of LINOLEIC ACID and is a coenzyme of oxoglutarate dehydrogenase (KETOGLUTARATE DEHYDROGENASE COMPLEX). It is used in DIETARY SUPPLEMENTS.

Chemical Identity

Chemical Information

Molecular Formula
C8H14O2S2
Molecular Weight
206.3 g/mol
CAS Registry No.
1077-28-7
IUPAC Name
5-(dithiolan-3-yl)pentanoic acid
InChIKey
AGBQKNBQESQNJD-UHFFFAOYSA-N
SMILES
C1CSSC1CCCCC(=O)O
MeSH Unique ID
D008063
Source
PubChem CID 864

MeSH Record

Classification

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

58 entry terms
  • Lipoic Acid
  • alpha-Lipoic Acid
  • Acid, alpha-Lipoic
  • alpha Lipoic Acid
  • Alpha-Lipogamma
  • Alpha-Lipon Stada
  • Alpha-Liponsaure Sofotec
  • Alpha-Lippon AL
  • Alphaflam
  • Azulipont
  • Fenint
  • Juthiac
  • Liponsaure-ratiopharm
  • MTW-Alphaliponsaure
  • Neurium
  • Pleomix-Alpha
  • Pleomix-Alpha N
  • Thioctacid
  • Thioctacide T
  • Thiogamma Injekt
  • Thiogamma oral
  • Tromlipon
  • Verla-Lipon
  • alpha-Liponaure Heumann
  • alpha-Liponsaure von ct
  • alpha-Vibolex
  • biomo-lipon
  • duralipon
  • espa-lipon
  • Alpha Lipogamma
  • Alpha Lipon Stada
  • Alpha Liponsaure Sofotec
  • Alpha Lippon AL
  • AlphaLipogamma
  • AlphaLipon Stada
  • AlphaLiponsaure Sofotec
  • AlphaLippon AL
  • Injekt, Thiogamma
  • Liponsaure ratiopharm
  • Liponsaureratiopharm
  • MTW Alphaliponsaure
  • MTWAlphaliponsaure
  • Pleomix Alpha
  • Pleomix Alpha N
  • PleomixAlpha
  • PleomixAlpha N
  • Verla Lipon
  • VerlaLipon
  • alpha Liponaure Heumann
  • alpha Liponsaure von ct
  • alpha Vibolex
  • alphaLiponaure Heumann
  • alphaLiponsaure von ct
  • alphaVibolex
  • biomo lipon
  • biomolipon
  • espa lipon
  • espalipon

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

91; was LIPOIC ACID 1963-90

MeSH Hierarchy

Tree Numbers

MeSH Record

NLM Classification

QU 135

AMA Style

References

  1. National Library of Medicine. Thioctic Acid. Medical Subject Headings (MeSH). 2026. Unique ID D008063. http://id.nlm.nih.gov/mesh/2026/D008063
  2. Thioctic Acid. In: Wikipedia. https://en.wikipedia.org/wiki/Lipoic_acid
  3. Thioctic Acid. In: Wikidata. https://www.wikidata.org/wiki/Q312229
  4. Thioctic Acid. In: PubChem Compound. CID 864. https://pubchem.ncbi.nlm.nih.gov/compound/864