Structured Summary
Abstract
3-((4-Amino-2-methyl-5-pyrimidinyl)methyl)-4-methyl-5-(4,6,8,8-tetrahydroxy-3,5,7-trioxa-4,6,8-triphosphaoct-1-yl)thiazolium hydroxide, inner salt, P,P',P''-trioxide. The triphosphate ester of thiamine. In Leigh's disease, this compound is present in decreased amounts in the brain due to a metabolic block in its formation.
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Drug Class
Pharmacological Action
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Synonyms
3 entry terms
- Thiamin Triphosphate
- Triphosphate, Thiamin
- Triphosphate, Thiamine
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Aspects Covered
29 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
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Indexing Annotation
do not confuse with THIAMIN TRIPHOSPHATASE; deficiency: coordinate THIAMINE TRIPHOSPHATE /defic (IM) with THIAMINE DEFICIENCY (IM)
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History Note
91(79); was see under THIAMINE 1979-90
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Previous Indexing
- Organophosphorus Compounds (1971-1978)
- Thiamine (1966-1978)
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AMA Style
References
- National Library of Medicine. Thiamine Triphosphate. Medical Subject Headings (MeSH). 2026. Unique ID D013838. http://id.nlm.nih.gov/mesh/2026/D013838
- Thiamine Triphosphate. In: Wikipedia. https://en.wikipedia.org/wiki/Thiamine_triphosphate
- Thiamine Triphosphate. In: Wikidata. https://www.wikidata.org/wiki/Q3523978