Structured Summary
Abstract
2-Substituted benzimidazole first introduced in 1962. It is active against a variety of nematodes and is the drug of choice for STRONGYLOIDIASIS. It has CENTRAL NERVOUS SYSTEM side effects and hepatototoxic potential. (From Smith and Reynard, Textbook of Pharmacology, 1992, p919)
Chemical Identity
Chemical Information
- Molecular Formula
- C10H7N3S
- Molecular Weight
- 201.25 g/mol
- CAS Registry No.
- 148-79-8
- IUPAC Name
- 4-(1H-benzimidazol-2-yl)-1,3-thiazole
- InChIKey
- WJCNZQLZVWNLKY-UHFFFAOYSA-N
- SMILES
- C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3
- MeSH Unique ID
- D013827
- Source
- PubChem CID 5430
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
6 entry terms
- 2-(4'-Thiazolyl)Benzimidazole
- Thibendole
- Tiabendazol
- Mintesol
- Mintezol
- Omnizole
MeSH Record
Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
65(63)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Thiabendazole. Medical Subject Headings (MeSH). 2026. Unique ID D013827. http://id.nlm.nih.gov/mesh/2026/D013827
- Thiabendazole. In: Wikipedia. https://en.wikipedia.org/wiki/Tiabendazole
- Thiabendazole. In: Wikidata. https://www.wikidata.org/wiki/Q424986
- Thiabendazole. In: PubChem Compound. CID 5430. https://pubchem.ncbi.nlm.nih.gov/compound/5430