Chemicals and Drugs

Thebaine

A drug that is derived from opium, which contains from 0.3-1.5% thebaine depending on its origin. It produces strychnine-like convulsions rather than narcosis. It may be habit-forming and is a controlled substance (opiate) listed in the U.S. Code of Federal Regulations, Title 21 Part 1308.12 (1985). (From Merck Index, 11th ed)

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A drug that is derived from opium, which contains from 0.3-1.5% thebaine depending on its origin. It produces strychnine-like convulsions rather than narcosis. It may be habit-forming and is a controlled substance (opiate) listed in the U.S. Code of Federal Regulations, Title 21 Part 1308.12 (1985). (From Merck Index, 11th ed)

Chemical Identity

Chemical Information

Molecular Formula
C19H21NO3
Molecular Weight
311.4 g/mol
CAS Registry No.
115-37-7
IUPAC Name
(4R,7aR,12bS)-7,9-dimethoxy-3-methyl-2,4,7a,13-tetrahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline
InChIKey
FQXXSQDCDRQNQE-VMDGZTHMSA-N
SMILES
CN1CC[C@]23[C@@H]4C(=CC=C2[C@H]1CC5=C3C(=C(C=C5)OC)O4)OC
MeSH Unique ID
D013797
Source
PubChem CID 5324289

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

Indexing Annotation

thebaine derivatives = THEBAINE /analogs

MeSH Record

History Note

THEBAINE DERIVATIVES was see under THEBAINE 1975-77; was see under MORPHINANS 1969-74

MeSH Hierarchy

Tree Numbers

  1. D03w.132w.577.249.562.856w
  2. D03w.605.497.607.851w
  3. D03w.633.400.686.607.851w
  4. D04w.615w.723w.795.576.856w

MeSH Record

NLM Classification

QV 92

AMA Style

References

  1. National Library of Medicine. Thebaine. Medical Subject Headings (MeSH). 2026. Unique ID D013797. http://id.nlm.nih.gov/mesh/2026/D013797
  2. Thebaine. In: Wikipedia. https://en.wikipedia.org/wiki/Thebaine
  3. Thebaine. In: Wikidata. https://www.wikidata.org/wiki/Q410169
  4. Thebaine. In: PubChem Compound. CID 5324289. https://pubchem.ncbi.nlm.nih.gov/compound/5324289