Anatomy

Th1 Cells

A subset of helper-inducer T-lymphocytes which synthesize and secrete INTERLEUKIN-2; INTERFERON-GAMMA; and INTERLEUKIN-12. Due to their ability to kill antigen-presenting cells and their lymphokine-mediated effector activity, Th1 cells are associated with vigorous delayed-type hypersensitivity reactions.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A subset of helper-inducer T-lymphocytes which synthesize and secrete INTERLEUKIN-2; INTERFERON-GAMMA; and INTERLEUKIN-12. Due to their ability to kill antigen-presenting cells and their lymphokine-mediated effector activity, Th1 cells are associated with vigorous delayed-type hypersensitivity reactions.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

10 entry terms
  • T Helper 1 Cells
  • TH-1 Cells
  • Type 1 Helper T Cells
  • Cell, TH-1
  • Cell, Th1
  • Cells, TH-1
  • Cells, Th1
  • TH 1 Cells
  • TH-1 Cell
  • Th1 Cell

MeSH Record

Aspects Covered

15 allowable subheadings

Indexed with the subheadings chemistry, classification, cytology, drug effects, enzymology, immunology, metabolism, microbiology, parasitology, pathology, physiology, radiation effects, transplantation, ultrastructure, virology.

MeSH Record

History Note

95

MeSH Record

Previous Indexing

  • T-Lymphocyte Subsets (1991-1994)
  • T-Lymphocytes, Helper-Inducer (1985-1994)

MeSH Hierarchy

Tree Numbers

  1. A11w.118w.637w.555w.567w.550.500.400.900
  2. A11w.118w.637w.555w.567w.569w.200w.400.900
  3. A11w.118w.637w.555w.567w.569w.500.400.900
  4. A15.145w.229w.637w.555w.567w.550.500.400.500
  5. A15.145w.229w.637w.555w.567w.569w.200w.400.500
  6. A15.145w.229w.637w.555w.567w.569w.500.400.500
  7. A15.382w.490w.555w.567w.550.500.400.900
  8. A15.382w.490w.555w.567w.569w.200w.400.900
  9. A15.382w.490w.555w.567w.569w.500.400.900

AMA Style

References

  1. National Library of Medicine. Th1 Cells. Medical Subject Headings (MeSH). 2026. Unique ID D018417. http://id.nlm.nih.gov/mesh/2026/D018417
  2. Th1 Cells. In: Wikidata. https://www.wikidata.org/wiki/Q11250619