Chemicals and Drugs

Tetrabenazine

A drug formerly used as an antipsychotic and treatment of various movement disorders. Tetrabenazine blocks neurotransmitter uptake into adrenergic storage vesicles and has been used as a high affinity label for the vesicle transport system.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A drug formerly used as an antipsychotic and treatment of various movement disorders. Tetrabenazine blocks neurotransmitter uptake into adrenergic storage vesicles and has been used as a high affinity label for the vesicle transport system.

Chemical Identity

Chemical Information

Molecular Formula
C19H27NO3
Molecular Weight
317.4 g/mol
CAS Registry No.
58-46-8
IUPAC Name
9,10-dimethoxy-3-(2-methylpropyl)-1,3,4,6,7,11b-hexahydrobenzo[a]quinolizin-2-one
InChIKey
MKJIEFSOBYUXJB-UHFFFAOYSA-N
SMILES
CC(C)CC1CN2CCC3=CC(=C(C=C3C2CC1=O)OC)OC
MeSH Unique ID
D013747
Source
PubChem CID 6018

MeSH Record

Classification

Broader headings

Related Concepts

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

2 entry terms
  • Nitoman
  • Xenazine

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Hierarchy

Tree Number

AMA Style

References

  1. National Library of Medicine. Tetrabenazine. Medical Subject Headings (MeSH). 2026. Unique ID D013747. http://id.nlm.nih.gov/mesh/2026/D013747
  2. Tetrabenazine. In: Wikipedia. https://en.wikipedia.org/wiki/Tetrabenazine
  3. Tetrabenazine. In: Wikidata. https://www.wikidata.org/wiki/Q413050
  4. Tetrabenazine. In: PubChem Compound. CID 6018. https://pubchem.ncbi.nlm.nih.gov/compound/6018