Phenomena and Processes

Tertiary Protein Structure

The level of protein structure in which combinations of secondary protein structures (ALPHA HELICES; BETA SHEETS; loop regions, and AMINO ACID MOTIFS) pack together to form folded shapes. Disulfide bridges between cysteines in two different parts of the polypeptide chain along with other interactions between the chains play a role in the formation and stabilization of tertiary structure.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

The level of protein structure in which combinations of secondary protein structures (ALPHA HELICES; BETA SHEETS; loop regions, and AMINO ACID MOTIFS) pack together to form folded shapes. Disulfide bridges between cysteines in two different parts of the polypeptide chain along with other interactions between the chains play a role in the formation and stabilization of tertiary structure.

MeSH Record

Classification

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MeSH Record

Synonyms

3 entry terms
  • Protein Structure, Tertiary
  • Protein Structures, Tertiary
  • Tertiary Protein Structures

MeSH Record

Aspects Covered

4 allowable subheadings

Indexed with the subheadings drug effects, genetics, physiology, radiation effects.

MeSH Record

Indexing Annotation

IM general only; coordinate NIM with specific protein

MeSH Record

History Note

93

MeSH Record

Previous Indexing

  • Protein Conformation (1972-1992)
  • Proteins (1966-1971)

MeSH Hierarchy

Tree Number

  1. G02.111.570.820w.709.610w

AMA Style

References

  1. National Library of Medicine. Tertiary Protein Structure. Medical Subject Headings (MeSH). 2026. Unique ID D017434. http://id.nlm.nih.gov/mesh/2026/D017434
  2. Tertiary Protein Structure. In: Wikipedia. https://en.wikipedia.org/wiki/Protein_tertiary_structure
  3. Tertiary Protein Structure. In: Wikidata. https://www.wikidata.org/wiki/Q898483