Structured Summary
Abstract
A naphthalene derivative that inhibits fungal SQUALENE EPOXIDASE and is used to treat DERMATOMYCOSES of the skin and nails.
Chemical Identity
Chemical Information
- Molecular Formula
- C21H25N
- Molecular Weight
- 291.4 g/mol
- CAS Registry No.
- 91161-71-6
- IUPAC Name
- (E)-N,6,6-trimethyl-N-(naphthalen-1-ylmethyl)hept-2-en-4-yn-1-amine
- InChIKey
- DOMXUEMWDBAQBQ-WEVVVXLNSA-N
- SMILES
- CC(C)(C)C#C/C=C/CN(C)CC1=CC=CC2=CC=CC=C21
- MeSH Unique ID
- D000077291
- Source
- PubChem CID 1549008
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
14 entry terms
- (E)-N-(6,6-Dimethyl-2-heptenynyl)-N-methyl-1-naphthalenementhamin hydrochloride
- DA 5505
- Lamisil
- SF 86-327
- SF-86-327
- TDT-067
- Terbinafine Hydrochloride
- Terbinafine, (Z)-
- Terbinafine, (Z)-isomer
- SF 86 327
- SF 86327
- SF86327
- TDT 067
- TDT067
MeSH Record
Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
2019 (1984)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Terbinafine. Medical Subject Headings (MeSH). 2026. Unique ID D000077291. http://id.nlm.nih.gov/mesh/2026/D000077291
- Terbinafine. In: Wikipedia. https://en.wikipedia.org/wiki/Terbinafine
- Terbinafine. In: Wikidata. https://www.wikidata.org/wiki/Q415259
- Terbinafine. In: PubChem Compound. CID 1549008. https://pubchem.ncbi.nlm.nih.gov/compound/1549008