Chemicals and Drugs

Tegafur

Congener of FLUOROURACIL with comparable antineoplastic action. It has been suggested especially for the treatment of breast neoplasms.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Congener of FLUOROURACIL with comparable antineoplastic action. It has been suggested especially for the treatment of breast neoplasms.

Chemical Identity

Chemical Information

Molecular Formula
C8H9FN2O3
Molecular Weight
200.17 g/mol
CAS Registry No.
17902-23-7
IUPAC Name
5-fluoro-1-(oxolan-2-yl)pyrimidine-2,4-dione
InChIKey
WFWLQNSHRPWKFK-UHFFFAOYSA-N
SMILES
C1CC(OC1)N2C=C(C(=O)NC2=O)F
MeSH Unique ID
D005641
Source
PubChem CID 5386

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

14 entry terms
  • 1-(2-Tetrahydrofuryl)-5-fluorouracil
  • 1-(Tetrahydro-2-furanyl)-5-fluorouracil
  • 5-Fluoro-1-(tetrahydro-2-furanyl)-2,4-pyrimidinedione
  • N1-(2'-Tetrahydrofuryl)-5-fluorouracil
  • FT-207
  • FT207
  • Florafur
  • Fluorofur
  • Ftorafur
  • Futraful
  • Sunfural S
  • Uftoral
  • Utefos
  • FT 207

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

91(77); was FTORAFUR 1986-90 & FTORAFUR see under FLUOROURACIL 1977-85

MeSH Record

Previous Indexing

  • Fluorouracil (1972-1976)
  • Furans (1972-1976)

MeSH Hierarchy

Tree Number

  1. D03w.383.742.698.875w.404w.850w

MeSH Record

NLM Classification

QV 269

AMA Style

References

  1. National Library of Medicine. Tegafur. Medical Subject Headings (MeSH). 2026. Unique ID D005641. http://id.nlm.nih.gov/mesh/2026/D005641
  2. Tegafur. In: Wikipedia. https://en.wikipedia.org/wiki/Tegafur
  3. Tegafur. In: Wikidata. https://www.wikidata.org/wiki/Q413370
  4. Tegafur. In: PubChem Compound. CID 5386. https://pubchem.ncbi.nlm.nih.gov/compound/5386