Chemicals and Drugs

Technetium Tc 99m Pyrophosphate

A radionuclide imaging agent used primarily in scintigraphy or tomography of the heart to evaluate the extent of the necrotic myocardial process. It has also been used in noninvasive tests for the distribution of organ involvement in different types of amyloidosis and for the evaluation of muscle necrosis in the extremities.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A radionuclide imaging agent used primarily in scintigraphy or tomography of the heart to evaluate the extent of the necrotic myocardial process. It has also been used in noninvasive tests for the distribution of organ involvement in different types of amyloidosis and for the evaluation of muscle necrosis in the extremities.

Chemical Identity

Chemical Information

Molecular Formula
O7P2Tc
Molecular Weight
272.85 g/mol
CAS Registry No.
52997-54-3
IUPAC Name
phosphonato phosphate;technetium-99(4+)
InChIKey
OOGKGVXDDGJCPO-IEOVAKBOSA-J
SMILES
[O-]P(=O)([O-])OP(=O)([O-])[O-].[99Tc+4]
MeSH Unique ID
D016698
Source
PubChem CID 6452753

MeSH Record

Classification

Broader headings

Related Concepts

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

9 entry terms
  • 99mTc-Pyrophosphate
  • Diphosphoric Acid, Technetium Salt
  • Tc 99m-Pyrophosphate
  • Tc-PYP
  • 99mTc Pyrophosphate
  • Tc 99m Pyrophosphate
  • Tc PYP
  • Technetium Tc 99m Pyrophosphate, Tc(3+) Salt (3:4)
  • Technetium Tc 99m Pyrophosphate, Tc(4+) Salt (1:1)

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

Indexing Annotation

for routine use as label, use no qualifiers

MeSH Record

History Note

92; was TECHNETIUM TC 99M PYROPHOSPHATE (NM) 1978-91

MeSH Record

Previous Indexing

  • Pyrophosphates (1966-1991)
  • Technetium (1966-1991)

MeSH Hierarchy

Tree Numbers

  1. D01w.029w.260.700.675.374w.775w.150w.900
  2. D01w.695.625.675.650w.775w.150w.900
  3. D01w.925.925

AMA Style

References

  1. National Library of Medicine. Technetium Tc 99m Pyrophosphate. Medical Subject Headings (MeSH). 2026. Unique ID D016698. http://id.nlm.nih.gov/mesh/2026/D016698
  2. Technetium Tc 99m Pyrophosphate. In: Wikidata. https://www.wikidata.org/wiki/Q22075867
  3. Technetium Tc 99m Pyrophosphate. In: PubChem Compound. CID 6452753. https://pubchem.ncbi.nlm.nih.gov/compound/6452753