Chemicals and Drugs

Tazobactam

A penicillanic acid and sulfone derivative and potent BETA-LACTAMASE inhibitor that enhances the activity of other anti-bacterial agents against beta-lactamase producing bacteria.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A penicillanic acid and sulfone derivative and potent BETA-LACTAMASE inhibitor that enhances the activity of other anti-bacterial agents against beta-lactamase producing bacteria.

Chemical Identity

Chemical Information

Molecular Formula
C10H12N4O5S
Molecular Weight
300.29 g/mol
CAS Registry No.
89786-04-9
IUPAC Name
(2S,3S,5R)-3-methyl-4,4,7-trioxo-3-(triazol-1-ylmethyl)-4lambda6-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
InChIKey
LPQZKKCYTLCDGQ-WEDXCCLWSA-N
SMILES
C[C@@]1([C@@H](N2[C@H](S1(=O)=O)CC2=O)C(=O)O)CN3C=CN=N3
MeSH Unique ID
D000078142
Source
PubChem CID 123630

MeSH Record

Classification

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

5 entry terms
  • Tazobactam Sodium
  • YTR 830
  • YTR 830H
  • YTR-830
  • YTR830

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

2019 (1985)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Tazobactam. Medical Subject Headings (MeSH). 2026. Unique ID D000078142. http://id.nlm.nih.gov/mesh/2026/D000078142
  2. Tazobactam. In: Wikipedia. https://en.wikipedia.org/wiki/Tazobactam
  3. Tazobactam. In: Wikidata. https://www.wikidata.org/wiki/Q423376
  4. Tazobactam. In: PubChem Compound. CID 123630. https://pubchem.ncbi.nlm.nih.gov/compound/123630