Chemicals and Drugs

Tapentadol

An opioid analgesic, MU OPIOID RECEPTOR agonist, and noradrenaline reuptake inhibitor that is used in the treatment of moderate to severe pain, and of pain associated with DIABETIC NEUROPATHIES.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An opioid analgesic, MU OPIOID RECEPTOR agonist, and noradrenaline reuptake inhibitor that is used in the treatment of moderate to severe pain, and of pain associated with DIABETIC NEUROPATHIES.

Chemical Identity

Chemical Information

Molecular Formula
C14H23NO
Molecular Weight
221.34 g/mol
CAS Registry No.
175591-23-8
IUPAC Name
3-[(2R,3R)-1-(dimethylamino)-2-methylpentan-3-yl]phenol
InChIKey
KWTWDQCKEHXFFR-SMDDNHRTSA-N
SMILES
CC[C@@H](C1=CC(=CC=C1)O)[C@@H](C)CN(C)C
MeSH Unique ID
D000077432
Source
PubChem CID 9838022

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

3 entry terms
  • 3-((1R,2R)-3-(dimethylamino)-1-ethyl-2-methylpropyl)phenol
  • Nucynta
  • Tapentadol Hydrochloride

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

2019 (2007)

MeSH Hierarchy

Tree Number

AMA Style

References

  1. National Library of Medicine. Tapentadol. Medical Subject Headings (MeSH). 2026. Unique ID D000077432. http://id.nlm.nih.gov/mesh/2026/D000077432
  2. Tapentadol. In: Wikipedia. https://en.wikipedia.org/wiki/Tapentadol
  3. Tapentadol. In: Wikidata. https://www.wikidata.org/wiki/Q414463
  4. Tapentadol. In: PubChem Compound. CID 9838022. https://pubchem.ncbi.nlm.nih.gov/compound/9838022