Chemicals and Drugs

Talin

A 235-kDa cytoplasmic protein that is also found in platelets. It has been localized to regions of cell-substrate adhesion. It binds to INTEGRINS; VINCULIN; and ACTINS and appears to participate in generating a transmembrane connection between the extracellular matrix and the cytoskeleton.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A 235-kDa cytoplasmic protein that is also found in platelets. It has been localized to regions of cell-substrate adhesion. It binds to INTEGRINS; VINCULIN; and ACTINS and appears to participate in generating a transmembrane connection between the extracellular matrix and the cytoskeleton.

MeSH Record

Classification

Broader headings

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MeSH Record

Synonyms

4 entry terms
  • Band 2 Protein
  • Protein, Band 2
  • Platelet Protein p235
  • Protein p235, Platelet

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

Indexing Annotation

a cytoplasmic protein; /drug eff /ultrastruct permitted

MeSH Record

History Note

92; was TALIN (NM) 1984-91

MeSH Record

Previous Indexing

  • Blood Proteins (1984-1986)
  • Contractile Proteins (1982-1986)
  • Cytoskeletal Proteins (1985-1991)
  • Muscle Proteins (1984-1986)

MeSH Hierarchy

Tree Number

AMA Style

References

  1. National Library of Medicine. Talin. Medical Subject Headings (MeSH). 2026. Unique ID D016608. http://id.nlm.nih.gov/mesh/2026/D016608
  2. Talin. In: Wikipedia. https://en.wikipedia.org/wiki/Talin_(protein)
  3. Talin. In: Wikidata. https://www.wikidata.org/wiki/Q7679528