Chemicals and Drugs

Tacrolimus Binding Protein 1A

A 12-KDa tacrolimus binding protein that is found associated with and may modulate the function of calcium release channels. It is a peptidyl-prolyl cis/trans isomerase which is inhibited by both tacrolimus (commonly called FK506) and SIROLIMUS.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A 12-KDa tacrolimus binding protein that is found associated with and may modulate the function of calcium release channels. It is a peptidyl-prolyl cis/trans isomerase which is inhibited by both tacrolimus (commonly called FK506) and SIROLIMUS.

MeSH Record

Classification

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MeSH Record

Synonyms

9 entry terms
  • FK506-Binding Protein 1
  • FK506-Binding Protein 1A
  • FKBP-12
  • FKBP12
  • Macrophilin-12
  • FK506 Binding Protein 1
  • FK506 Binding Protein 1A
  • FKBP 12
  • Macrophilin 12

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2001; use TACROLIMUS BINDING PROTEINS (NM) 1991-2000

MeSH Record

Previous Indexing

  • Carrier Proteins (1991-1998)
  • DNA-Binding Proteins (1991-1998)
  • Heat-Shock Proteins (1991-1998)
  • Immunophilins (1999-2000)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Tacrolimus Binding Protein 1A. Medical Subject Headings (MeSH). 2026. Unique ID D022061. http://id.nlm.nih.gov/mesh/2026/D022061
  2. Tacrolimus Binding Protein 1A. In: Wikidata. https://www.wikidata.org/wiki/Q78334636