Structured Summary
Abstract
An RNA-binding protein characterized by three RNA RECOGNITION MOTIFS. It binds to AU RICH ELEMENTS in the 3'-untranslated regions of mRNA and regulates alternative pre-RNA splicing and mRNA translation; it may also function in APOPTOSIS. Mutations in the TIA-1 gene are associated with WELANDER DISTAL MYOPATHY.
MeSH Record
Classification
Related Concepts
Knowledge Graph
Drag nodes to rearrange; hover to trace links; click a node to open its page.
MeSH Record
Synonyms
8 entry terms
- RNA-Binding Protein TIA-1
- T-Cell-Restricted Intracellular Antigen-1
- Intracellular Antigen-1, T-Cell
- Intracellular Antigen-1, T-Cell-Restricted
- RNA Binding Protein TIA 1
- T Cell Intracellular Antigen 1
- T Cell Restricted Intracellular Antigen 1
- TIA-1, RNA-Binding Protein
MeSH Record
Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2018
MeSH Record
Previous Indexing
- RNA-Binding Proteins (1991-2017)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. T-Cell Intracellular Antigen-1. Medical Subject Headings (MeSH). 2026. Unique ID D000074019. http://id.nlm.nih.gov/mesh/2026/D000074019
- T-Cell Intracellular Antigen-1. In: Wikipedia. https://en.wikipedia.org/wiki/TIA1
- T-Cell Intracellular Antigen-1. In: Wikidata. https://www.wikidata.org/wiki/Q21123939