Structured Summary
Abstract
A basic helix-loop-helix transcription factor that plays a critical role in HEMATOPOIESIS and as a positive regulator in the differentiation of ERYTHROID CELLS. Chromosome translocations involving the TAL-1 gene are associated with T-CELL ACUTE LYMPHOCYTIC LEUKEMIA.
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Classification
Broader headings
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MeSH Record
Synonyms
5 entry terms
- TAL-1 Protein
- TAL1 Transcription Factor
- T Cell Acute Lymphocytic Leukemia Protein 1
- TAL 1 Protein
- Transcription Factor, TAL1
MeSH Record
Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2018
MeSH Record
Previous Indexing
- Basic Helix-Loop-Helix Transcription Factors (2005-2017)
- Proto-Oncogene Proteins (2005-2017)
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AMA Style
References
- National Library of Medicine. T-Cell Acute Lymphocytic Leukemia Protein 1. Medical Subject Headings (MeSH). 2026. Unique ID D000073942. http://id.nlm.nih.gov/mesh/2026/D000073942
- T-Cell Acute Lymphocytic Leukemia Protein 1. In: Wikidata. https://www.wikidata.org/wiki/Q7669284