Diseases

Systemic Scleroderma

A chronic multi-system disorder of CONNECTIVE TISSUE. It is characterized by SCLEROSIS in the SKIN, the LUNGS, the HEART, the GASTROINTESTINAL TRACT, the KIDNEYS, and the MUSCULOSKELETAL SYSTEM. Other important features include diseased small BLOOD VESSELS and AUTOANTIBODIES. The disorder is named for its most prominent feature (hard skin), and classified into subsets by the extent of skin thickening: LIMITED SCLERODERMA and DIFFUSE SCLERODERMA.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A chronic multi-system disorder of CONNECTIVE TISSUE. It is characterized by SCLEROSIS in the SKIN, the LUNGS, the HEART, the GASTROINTESTINAL TRACT, the KIDNEYS, and the MUSCULOSKELETAL SYSTEM. Other important features include diseased small BLOOD VESSELS and AUTOANTIBODIES. The disorder is named for its most prominent feature (hard skin), and classified into subsets by the extent of skin thickening: LIMITED SCLERODERMA and DIFFUSE SCLERODERMA.

MeSH Record

Classification

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MeSH Record

Synonyms

3 entry terms
  • Scleroderma, Systemic
  • Sclerosis, Systemic
  • Systemic Sclerosis

MeSH Record

Aspects Covered

35 allowable subheadings

Indexed with the subheadings blood, cerebrospinal fluid, chemically induced, classification, complications, congenital, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, urine, veterinary, virology.

MeSH Record

Indexing Annotation

note specific indentations and SCLERODERMA, LOCALIZED

MeSH Record

History Note

1971

MeSH Hierarchy

Tree Numbers

MeSH Record

NLM Classification

WR 260

AMA Style

References

  1. National Library of Medicine. Systemic Scleroderma. Medical Subject Headings (MeSH). 2026. Unique ID D012595. http://id.nlm.nih.gov/mesh/2026/D012595
  2. Systemic Scleroderma. In: Wikipedia. https://en.wikipedia.org/wiki/Systemic_scleroderma
  3. Systemic Scleroderma. In: Wikidata. https://www.wikidata.org/wiki/Q5340515