Diseases

Systemic Lupus Erythematosus

A chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the skin, joints, kidneys, and serosal membranes. It is of unknown etiology, but is thought to represent a failure of the regulatory mechanisms of the autoimmune system. The disease is marked by a wide range of system dysfunctions, an elevated erythrocyte sedimentation rate, and the formation of LE cells in the blood or bone marrow.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the skin, joints, kidneys, and serosal membranes. It is of unknown etiology, but is thought to represent a failure of the regulatory mechanisms of the autoimmune system. The disease is marked by a wide range of system dysfunctions, an elevated erythrocyte sedimentation rate, and the formation of LE cells in the blood or bone marrow.

MeSH Record

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MeSH Record

See Also

MeSH Record

Synonyms

5 entry terms
  • Lupus Erythematosus Disseminatus
  • Lupus Erythematosus, Systemic
  • Libman-Sacks Disease
  • Disease, Libman-Sacks
  • Libman Sacks Disease

MeSH Record

Aspects Covered

35 allowable subheadings

Indexed with the subheadings blood, cerebrospinal fluid, chemically induced, classification, complications, congenital, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, urine, veterinary, virology.

MeSH Record

Indexing Annotation

if not specified as "systemic" it is still probably correct to index here, not also discoid; LE CELLS see NEUTROPHILS is also available

MeSH Hierarchy

Tree Numbers

  1. C17.300w.480w
  2. C20w.111w.590w

MeSH Record

NLM Classification

QZ 194

AMA Style

References

  1. National Library of Medicine. Systemic Lupus Erythematosus. Medical Subject Headings (MeSH). 2026. Unique ID D008180. http://id.nlm.nih.gov/mesh/2026/D008180
  2. Systemic Lupus Erythematosus. In: Wikipedia. https://en.wikipedia.org/wiki/Lupus
  3. Systemic Lupus Erythematosus. In: Wikidata. https://www.wikidata.org/wiki/Q1485