Phenomena and Processes

Synthetic Lethal Mutations

Mutations in genes which lead to cell or organism death when occurring in combination with mutations in one or more other genes.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Mutations in genes which lead to cell or organism death when occurring in combination with mutations in one or more other genes.

MeSH Record

Classification

Broader headings

Related Concepts

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See Also

MeSH Record

Synonyms

7 entry terms
  • Synthetic Lethal Mutation
  • Lethal Mutation, Synthetic
  • Lethal Mutations, Synthetic
  • Mutation, Synthetic Lethal
  • Mutations, Synthetic Lethal
  • Synthetic Lethality
  • Lethality, Synthetic

MeSH Record

Aspects Covered

5 allowable subheadings

Indexed with the subheadings drug effects, genetics, immunology, physiology, radiation effects.

MeSH Record

History Note

2017

MeSH Hierarchy

Tree Number

  1. G05.365w.590w.917w

AMA Style

References

  1. National Library of Medicine. Synthetic Lethal Mutations. Medical Subject Headings (MeSH). 2026. Unique ID D000072020. http://id.nlm.nih.gov/mesh/2026/D000072020
  2. Synthetic Lethal Mutations. In: Wikipedia. https://en.wikipedia.org/wiki/Synthetic_lethality
  3. Synthetic Lethal Mutations. In: Wikidata. https://www.wikidata.org/wiki/Q7662767