Chemicals and Drugs

Synaptotagmin I

A vesicular transport protein expressed predominately in NEURONS. Synaptotagmin helps regulate EXOCYTOSIS of SYNAPTIC VESICLES and appears to serve as a calcium sensor to trigger NEUROTRANSMITTER release. It also acts as a nerve cell receptor for certain BOTULINUM TOXINS.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A vesicular transport protein expressed predominately in NEURONS. Synaptotagmin helps regulate EXOCYTOSIS of SYNAPTIC VESICLES and appears to serve as a calcium sensor to trigger NEUROTRANSMITTER release. It also acts as a nerve cell receptor for certain BOTULINUM TOXINS.

MeSH Record

Classification

Broader headings

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MeSH Record

Synonyms

3 entry terms
  • Synaptic Vesicle Protein p65
  • Synaptotagmin 1
  • p65 Protein (Synaptotagmin I)

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2006(1991)

MeSH Hierarchy

Tree Numbers

  1. D12.776w.157w.125w.825w.249
  2. D12.776w.543w.990w.850w.249

AMA Style

References

  1. National Library of Medicine. Synaptotagmin I. Medical Subject Headings (MeSH). 2026. Unique ID D050863. http://id.nlm.nih.gov/mesh/2026/D050863
  2. Synaptotagmin I. In: Wikidata. https://www.wikidata.org/wiki/Q21171815