Phenomena and Processes

Suppressor Genes

Genes that have a suppressor allele or suppressor mutation (SUPPRESSION, GENETIC) which cancels the effect of a previous mutation, enabling the wild-type phenotype to be maintained or partially restored. For example, amber suppressors cancel the effect of an AMBER NONSENSE MUTATION.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Genes that have a suppressor allele or suppressor mutation (SUPPRESSION, GENETIC) which cancels the effect of a previous mutation, enabling the wild-type phenotype to be maintained or partially restored. For example, amber suppressors cancel the effect of an AMBER NONSENSE MUTATION.

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Classification

Broader headings

Related Concepts

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See Also

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Synonyms

37 entry terms
  • Genes, Second-Site Suppressor
  • Genes, Suppressor
  • Second-Site Suppressor Genes
  • Gene, Second-Site Suppressor
  • Gene, Suppressor
  • Genes, Second Site Suppressor
  • Second Site Suppressor Genes
  • Second-Site Suppressor Gene
  • Suppressor Gene
  • Suppressor Gene, Second-Site
  • Suppressor Genes, Second-Site
  • Amber Suppressor Genes
  • Frameshift Suppressor Genes
  • Genes, Amber Suppressor
  • Genes, Frameshift Suppressor
  • Genes, Nonsense Mutation Suppressor
  • Genes, Ochre Suppressor
  • Genes, Opal Suppressor
  • Nonsense Mutation Suppressor Genes
  • Ochre Suppressor Genes
  • Amber Suppressor Gene
  • Frameshift Suppressor Gene
  • Gene, Amber Suppressor
  • Gene, Frameshift Suppressor
  • Gene, Ochre Suppressor
  • Gene, Opal Suppressor
  • Ochre Suppressor Gene
  • Opal Suppressor Gene
  • Opal Suppressor Genes
  • Suppressor Gene, Amber
  • Suppressor Gene, Frameshift
  • Suppressor Gene, Ochre
  • Suppressor Gene, Opal
  • Suppressor Genes, Amber
  • Suppressor Genes, Frameshift
  • Suppressor Genes, Ochre
  • Suppressor Genes, Opal

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Aspects Covered

4 allowable subheadings

Indexed with the subheadings drug effects, ethics, physiology, radiation effects.

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Indexing Annotation

GENES, TUMOR SUPPRESSOR is also available; do not use for genes involved in suppression of a physiologic process: index the physiologic process /genet + specific gene if pertinent (genes involved in memory suppression = MEMORY /genet + specific gene term if pertinent but not GENES, SUPPRESSOR)

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History Note

91; was see SUPPRESSION, GENETIC 1980-90; was heading 1968-79 (Prov 1968-69)

MeSH Record

Previous Indexing

  • Genes, Suppressor (1968-1979)
  • Suppression, Genetic (1980-1990)

MeSH Hierarchy

Tree Number

  1. G05.360w.340w.024.340w.460

AMA Style

References

  1. National Library of Medicine. Suppressor Genes. Medical Subject Headings (MeSH). 2026. Unique ID D016153. http://id.nlm.nih.gov/mesh/2026/D016153
  2. Suppressor Genes. In: Wikidata. https://www.wikidata.org/wiki/Q71227721