Chemicals and Drugs

Sulfadoxine

A long acting sulfonamide that is used, usually in combination with other drugs, for respiratory, urinary tract, and malarial infections.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A long acting sulfonamide that is used, usually in combination with other drugs, for respiratory, urinary tract, and malarial infections.

Chemical Identity

Chemical Information

Molecular Formula
C12H14N4O4S
Molecular Weight
310.33 g/mol
CAS Registry No.
2447-57-6
IUPAC Name
4-amino-N-(5,6-dimethoxypyrimidin-4-yl)benzenesulfonamide
InChIKey
PJSFRIWCGOHTNF-UHFFFAOYSA-N
SMILES
COC1=C(N=CN=C1OC)NS(=O)(=O)C2=CC=C(C=C2)N
MeSH Unique ID
D013413
Source
PubChem CID 17134

MeSH Record

Classification

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

9 entry terms
  • Sulformethoxine
  • Sulformetoxine
  • Sulforthomidine
  • Sulphormetoxin
  • Sulphorthodimethoxine
  • Fanasil
  • Ro 4-4393
  • Ro 4 4393
  • Ro 44393

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

91(75); was see under SULFANILAMIDES 1975-90

MeSH Record

Previous Indexing

  • Pyrimidines (1971-1974)
  • Sulfonamides (1971-1974)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Sulfadoxine. Medical Subject Headings (MeSH). 2026. Unique ID D013413. http://id.nlm.nih.gov/mesh/2026/D013413
  2. Sulfadoxine. In: Wikipedia. https://en.wikipedia.org/wiki/Sulfadoxine
  3. Sulfadoxine. In: Wikidata. https://www.wikidata.org/wiki/Q411557
  4. Sulfadoxine. In: PubChem Compound. CID 17134. https://pubchem.ncbi.nlm.nih.gov/compound/17134