Structured Summary
Abstract
Enzymes that catalyze the first step leading to the oxidation of succinic acid by the reversible formation of succinyl-CoA from succinate and CoA with the concomitant cleavage of ATP to ADP (EC 6.2.1.5) or GTP to GDP (EC 6.2.1.4) and orthophosphate. Itaconate can act instead of succinate and ITP instead of GTP.EC 6.2.1.-.
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
Drag nodes to rearrange; hover to trace links; click a node to open its page.
MeSH Record
Synonyms
19 entry terms
- Succinate-CoA Ligase
- Succinic Thiokinase
- Succinic Thiokinases
- Succinyl CoA Synthetase
- Succinyl CoA Synthetases
- Succinyl Coenzyme A Synthetase
- Succinyl Coenzyme A Synthetases
- CoA Synthetase, Succinyl
- CoA Synthetases, Succinyl
- Ligase, Succinate-CoA
- Ligases, Succinate-CoA
- Succinate CoA Ligase
- Succinate CoA Ligases
- Synthetase, Succinyl CoA
- Synthetases, Succinyl CoA
- Thiokinase, Succinic
- Thiokinases, Succinic
- Succinate-CoA Ligase (GDP-Forming)
- Succinate-CoA Ligases (ADP-Forming)
MeSH Record
Aspects Covered
29 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
98(76)
MeSH Record
Previous Indexing
- Coenzyme A Synthetases (1973)
- Succinates (1973)
MeSH Hierarchy
Tree Number
AMA Style
References
- National Library of Medicine. Succinate-CoA Ligases. Medical Subject Headings (MeSH). 2026. Unique ID D013389. http://id.nlm.nih.gov/mesh/2026/D013389
- Succinate-CoA Ligases. In: Wikidata. https://www.wikidata.org/wiki/Q76384549