Anatomy

Substantia Nigra

The black substance in the ventral midbrain or the nucleus of cells containing the black substance. These cells produce DOPAMINE, an important neurotransmitter in regulation of the sensorimotor system and mood. The dark colored MELANIN is a by-product of dopamine synthesis.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

The black substance in the ventral midbrain or the nucleus of cells containing the black substance. These cells produce DOPAMINE, an important neurotransmitter in regulation of the sensorimotor system and mood. The dark colored MELANIN is a by-product of dopamine synthesis.

MeSH Record

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MeSH Record

Synonyms

3 entry terms
  • Nigra, Substantia
  • Nigras, Substantia
  • Substantia Nigras

MeSH Record

Aspects Covered

23 allowable subheadings

Indexed with the subheadings abnormalities, anatomy & histology, blood supply, chemistry, cytology, diagnostic imaging, drug effects, embryology, enzymology, growth & development, immunology, injuries, metabolism, microbiology, parasitology, pathology, physiology, physiopathology, radiation effects, surgery, transplantation, ultrastructure, virology.

MeSH Hierarchy

Tree Number

  1. A08w.186w.211w.132w.659w.413w.656w

MeSH Record

NLM Classification

WL 310

AMA Style

References

  1. National Library of Medicine. Substantia Nigra. Medical Subject Headings (MeSH). 2026. Unique ID D013378. http://id.nlm.nih.gov/mesh/2026/D013378
  2. Substantia Nigra. In: Wikipedia. https://en.wikipedia.org/wiki/Substantia_nigra
  3. Substantia Nigra. In: Wikidata. https://www.wikidata.org/wiki/Q753278