Chemicals and Drugs

Subfamily G Member 2 ATP Binding Cassette Transporter

ATP-binding cassette transporter, sub-family G protein that functions as a high capacity UREA exporter, transporter of STEROLS, and in the absorption and efflux of many drugs. Its efflux activity for ANTINEOPLASTIC AGENTS contributes to DRUG RESISTANCE. It functions as a homodimer and is expressed by cells in a variety of organs, as well as by NEOPLASTIC STEM CELLS.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

ATP-binding cassette transporter, sub-family G protein that functions as a high capacity UREA exporter, transporter of STEROLS, and in the absorption and efflux of many drugs. Its efflux activity for ANTINEOPLASTIC AGENTS contributes to DRUG RESISTANCE. It functions as a homodimer and is expressed by cells in a variety of organs, as well as by NEOPLASTIC STEM CELLS.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

5 entry terms
  • ABCG2 Protein
  • ABCG2 Transporter
  • ATP Binding Cassette Transporter, Sub-Family G, Member 2
  • ATP Binding Cassette Transporter, Subfamily G, Member 2
  • CD338 Antigen

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2019 (2017)

MeSH Record

Previous Indexing

  • ATP-Binding Cassette Transporters (1999-2016)

MeSH Hierarchy

Tree Numbers

  1. D09w.400w.430w.890w.020w.457.500
  2. D12.776w.157w.530w.100w.228.500
  3. D12.776w.395w.550w.020w.457.500
  4. D12.776w.543w.550w.192w.457.500
  5. D12.776w.543w.585w.100w.228.500

AMA Style

References

  1. National Library of Medicine. Subfamily G Member 2 ATP Binding Cassette Transporter. Medical Subject Headings (MeSH). 2026. Unique ID D000070997. http://id.nlm.nih.gov/mesh/2026/D000070997
  2. Subfamily G Member 2 ATP Binding Cassette Transporter. In: Wikidata. https://www.wikidata.org/wiki/Q24769503